Editorial

Los trabajos y opiniones que aquí se exponen son orientadores de lo que se publica en Cuba y en el mundo sobre aspectos relevantes de la hipertensión arterial.

Editorial
                      

Effect of Chlorthalidone, Amlodipine, and Lisinopril on Visit-to-Visit Variability of Blood Pressure: Results From the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.

Por:  Paul Muntner PhD, Emily B. Levitan PhD, Amy I. Lynch PhD, Lara M. Simpson PhD, Jeffrey Whittle MD, Barry R. Davis MD, PhD, John B. Kostis MD, Paul K. Whelton MD y Suzanne Oparil MD.  The Journal of Clinical Hypertension, volume 16, Issue 5, pages 323–330, May 2014.

Few randomized trials have compared visit-to-visit variability (VVV) of systolic blood pressure (SBP) across drug classes. The authors compared VVV of SBP among 24,004 participants randomized to chlorthalidone, amlodipine, or lisinopril in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). VVV of SBP was calculated across 5 to 7 visits occurring 6 to 28 months following randomization.

Artículos Originales

Knowledge of blood pressure in a UK general public population

Por: J Slark, M S Khan, P Bentley y P Sharma.  Journal of Human Hypertension (2014) 28, 500–503

journal-of-human-hypertensionLittle is known about the general public’s understanding of the role of blood pressure (BP) in contributing to heart disease and stroke. This study aimed to gain a wider understanding of the knowledge and awareness of BP in a selected London population. As part of a stroke awareness campaign, members of the public were offered BP testing and were asked about their knowledge and awareness of BP. Descriptive statistics were employed to explore knowledge and awareness of BP. ?2-test was run to explore the difference between knowledge and awareness of BP, and whether there was a difference in BP readings in normotensive and hypertensive participants. A total of 1019 participants (males 295; mean age 54 years, range 16–92) were recruited with a mean BP of 130/77 mmHg

Comentando

La Hipertensión Arterial y DOCTUS VIII. Algunas consideraciones

Por: Ing. Lisandra Nuñez Aguilar.   Revista Cubana de Cardiologia y Cirugía Cardiosvascular , Vol. 20, No. 1 (2014).

ComentadoLa hipertensión arterial HTA es una de las enfermedades que afecta más frecuentemente a la población adulta en el mundo. Numerosos estudios han demostrado que esta afección está presente en el 20 al 30 % de las personas mayores de 15 años.   Estudios realizados en Cuba han evidenciado una alta prevalencia de las enfermedades cardiovasculares, entre ellas, la HTA, estimándose que afecta a una tercera parte de la población adulta. En los últimos años, su incidencia y sus complicaciones cardiovasculares están aumentando notablemente, sobre todo por el progresivo envejecimiento de la población y el paulatino incremento de la esperanza de vida.

Factores de Riesgo

Antihypertensive drug classes have different effects on short-term blood pressure variability in essential hypertension

Riesgo cardiovascularPor: Natacha Levi-Marpillat, Isabelle Macquin-Mavier, Anne-Isabelle Tropeano, Gianfranco Parati y Patrick Maison.  Hypertension Research (2014) 37, 585–590.

Increased blood pressure variability (BPV) contributes to end-organ damage, cardiovascular events and mortality associated with hypertension. In a cohort of 2780 hypertensive patients treated by either calcium channel blockers (CCBs), diuretics, angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs) or ß-blockers alone or in combination, we compared indices of short-term BPV according to the different treatments. Short-term BPV was calculated as the standard deviation (s.d.) of 24?h, daytime or nighttime systolic blood pressure and diastolic blood pressure (SBP and DBP).

Revisiones sistemáticas

Sex differences in response to angiotensin II receptor blocker-based therapy in elderly, high-risk, hypertensive Japanese patients: a subanalysis of the OSCAR study

Revisiones sistematicasPor: Kunihiko Matsui, Shokei Kim-Mitsuyama, Hisao Ogawa, Tomio Jinnouchi, Hideaki Jinnouchi y Kikuo Arakawa for the OlmeSartan Calcium Antagonists Randomized (OSCAR) Study Group.  Hypertension Research (2014) 37, 526–532.

Essential hypertension is a common comorbid condition and risk factor for cardiovascular events; in addition to lifestyle modification, drug therapy is the main treatment strategy. Although there are indications for specific classes of antihypertensive drugs for particular patients, such as diuretics for hypertensive African Americans,1 there is no uniform agreement on the type of drug(s) that should be used when physicians choose an antihypertensive drug for newly diagnosed patients without specific indications for those drugs.  Recently, many evidence-based clinical practice guidelines from various clinical fields have been published to improve the quality of patient care.

Investigaciones

Ethnic differences in genetic predisposition to  hypertension

InvestigacionesPor: Norihiro Kato.  Hypertension Research (2012) 35, 574–581.

Genetic, environmental and demographic factors and their interaction determine an individual’s risk for hypertension. Despite considerable efforts to investigate the genetic basis of hypertension, or elevated blood pressure (BP) levels, the inherently complex nature hampered progress in the elucidation of the genes involved and yielded little success until 2009 when two consortia-based meta-analyses of genome-wide association (GWA) studies involving 30?000–40?000 samples in the discovery stage identified a total of 13 independent loci significantly associated with BP in populations of European descent.

Artículos interesantes

En esta sección les exponemos algunos artículos publicados sobre la hipertensión arterial.    

  De varias Revistas

 

Hypertension in Obese Type 2 Diabetes Patients is Associated with Increases in Insulin Resistance and IL-6 Cytokine Levels: Potential Targets for an Efficient Preventive Intervention
 

Por:  Ljiljana Lukic , Nebojsa M. Lalic, Natasa Rajkovic, Aleksandra Jotic, Katarina Lalic, Tanja Milicic, Jelena P. Seferovic, Marija Macesic y Jelena Stanarcic Gajovic.   Int. J. Environ. Res. Public Health 2014, 11(4), 3586-3598.

 

Decreased renal function in hypertensive emergencies
 

Por: U Derhaschnig, C Testori, E Riedmueller, E L Hobl, F B Mayr y  B Jilma.  Journal of Human Hypertension (2014) 28, 427–431.
 

 

El uso de los beta-bloqueadores y el Eighth Joint National Committee

 

Por: Alberto Morales Salinas.  Revista Finlay de enfermedadades no transmisibles, vol. 4, núm. 1 (2014).

 

 

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