Editorial

Los trabajos y opiniones que aquí se exponen son orientadores de lo que se publica en Cuba y en el mundo sobre aspectos relevantes de la hipertensión arterial.

Editorial


Novel treatment approaches in hypertensive type 2 diabetic patients

Por: Yaniel Castro Torres and Richard E Katholi. World J. Diabetes, 2014 August  15; 5(4): 536-545.

Type 2 diabetes mellitus (T2DM) and hypertension (HTN) represent two common conditions worldwide. They increase the risk for the development of cardiovascular diseases with adverse clinical outcomes including disabilities and mortality. The International Diabetes Federation reports that diabetes kills one person every six seconds and afflicts 382 million people worldwide. The federation estimates that the number of people affected by the disease is expected to climb to 592 million by 2035.
DM is a group of metabolic diseases characterized by impairment in glucose, lipid and protein metabolism, resulting from alterations in insulin secretion, insulin action or both. While four types of DM have been classified, T2DM is the most prevalent and accounts for 90% to 95% of all diagnosed cases.

Artículos Originales

Association between blood pressure and disability-free survival among community-dwelling elderly patients receiving  antihypertensive treatment

Revista Hypertension ResearchPor: Osamu Iritani, Yumi Koizumi, Yuko Hamazaki, Hiroshi Yano, Takuro Morita, Taroh Himeno, Tazuo Okuno, Masashi Okuro, Kunimitsu Iwai y  Shigeto Morimoto.   Hypertension Research (2014) 37, 772–778.

A reduction of elevated blood pressure (BP) is an important treatment goal in elderly hypertensive patients. However, excessive reduction of systolic BP (SBP) and/or diastolic BP (DBP) might be harmful in such patients. We investigated whether this was the case with regard to risk of incident disability or death in community-dwelling elderly subjects. Relationships among each of the four classes of SBP or DBP and the risk of incident disability or death were estimated using the Cox proportional hazards model. Over four years, 77 (13.5%) incident disabilities or deaths occurred.

Comentando

Effects of Immediate Blood Pressure Reduction on Death and Major Disability in Patients With Acute Ischemic Stroke

ComentadoPor: Jiang He, MD, PhD; Yonghong Zhang, MD, PhD; Tan Xu, MD, PhD; Qi Zhao, MD, PhD; Dali Wang, MD; Chung-Shiuan Chen, MS; Weijun Tong, MD; Changjie Liu, MD; Tian Xu, MD; Zhong Ju, MD; Yanbo Peng, MD; et al. Stroke is the second leading cause of death and the leading cause of serious, long-term disability worldwide.1 Clinical trials have documented that lowering blood pressure reduces the risk of stroke in hypertensive and normotensive patients with a history of stroke or transient ischemic attack. Although the benefit of lowering blood pressure for primary and secondary prevention of stroke has been established, the effect of immediate antihypertensive treatment in patients with acute ischemic stroke and elevated blood pressure is uncertain.  Elevated blood pressure is common during acute ischemic stroke.

Factores de Riesgo

Riesgo cardiovascular global en pacientes ancianos hipertensos

Riesgo cardiovascularPor: Asdrúbal Arias Morales, Ricardo Amador García Hernández y Maritza Oliva Pérez.  Rev Cubana Med. 2014;53(2).

La hipertensión arterial es la más común de las condiciones prevenibles que afecta la salud de los individuos adultos en las poblaciones de todas las regiones del mundo. Describir el riesgo cardiovascular global en pacientes hipertensos de la tercera edad así como su relación con factores de riesgo asociados.  Se realizó un estudio observacional, descriptivo y de corte transversal en pacientes hipertensos de la tercera edad, pertenecientes al Consultorio Médico de la Familia no. 2, del reparto Miraflores Nuevo, en el período comprendido entre octubre de 2009 y julio de 2010. Se constituyó una muestra de 65 pacientes a los que se les practicó examen clínico completo y dosificación sérica de colesterol.   Se concluye que en pacientes ancianos hipertensos, la diabetes mellitus, la tensión arterial sistólica ³ 160 mmHg y la edad ³ 70 años constituyen los factores de riesgo de mayor impacto en relación con el riesgo cardiovascular global.

Revisiones sistemáticas

Association between blood pressure and disability-free survival among community-dwelling elderly patients receiving  antihypertensive treatment

Revisiones sistematicasPor: Osamu Iritani, Yumi Koizumi, Yuko Hamazaki, Hiroshi Yano, Takuro Morita, Taroh Himeno, Tazuo Okuno, Masashi Okuro, Kunimitsu Iwai y  Shigeto Morimoto.   Hypertension Research (2014) 37, 772–778.

A reduction of elevated blood pressure (BP) is an important treatment goal in elderly hypertensive patients. However, excessive reduction of systolic BP (SBP) and/or diastolic BP (DBP) might be harmful in such patients. We investigated whether this was the case with regard to risk of incident disability or death in community-dwelling elderly subjects.

Investigaciones

Are There Any New Pharmacologic Therapies on the Horizon to Better Treat Hypertension?

InvestigacionesPor: Gabriel B. Habib, Sr, MS, MD, FACC, FCCP, FAHA, Sukhdeep S. Basra, MD, MPH.  J CARDIOVASC PHARMACOL THER May 1, 2014( 107).

Hypertension is the most important cardiovascular risk factor. We have witnessed a significant improvement in hypertension treatment and control and an impressive growth in the pharmacologic options available to clinicians and hypertension specialists. With up to a third of patients with hypertension not at the recommended goal blood pressures, it is critically important to develop novel therapeutic approaches to better treat hypertension.

Artículos intersantes

En esta sección les exponemos algunos artículos publicados sobre la hipertensión arterial.

3-articulos-interesantesRevista de: Hypertension Research

Effects of antihypertensive drugs on central blood pressure: new evidence, more challenges

Por: Giacomo Pucci, Francesca Battista y Giuseppe Schillaci.   Hypertension Research (2014) 37, 10–12.

High sodium augments angiotensin II-induced vascular smooth muscle cell proliferation through the ERK 1/2-dependent pathway

Por: Gang Liu, Hirofumi Hitomi, Asadur Rahman, Daisuke Nakano1, Hirohito Mori, Tsutomu Masaki, Hong Ma, Takahiro Iwamoto, Hiroyuki Kobori y Akira Nishiyama.   Hypertension Research (2014) 37, 13–18.

Efficacy of losartan and carvedilol on central hemodynamics in hypertensives: a prospective, randomized, open, blinded end point, multicenter study.

Por: Eung Ju Kim, Woo-Hyuk Song, Jae Ung Lee3, Mi-Seung Shin, Sahng Lee, Byeong-Ok Kim, Kyeong-Sun Hong, Seong Woo Han, Chang Gyu Park y Hong Seog Seo.  Hypertension Research (2014) 37, 50–56.